Name | 4,4'-DIACETAMIDODIPHENYLMETHANE |
Synonyms | BRD-K4477 FH1(BRD-K4477) 4,4'-DIACETAMIDODIPHENYLMETHANE N-[4-(4-acetamidobenzyl)phenyl]acetamide Acetamide,N,N'-(methylenedi-4,1-phenylene)bis- N-[4-[(4-acetamidophenyl)methyl]phenyl]acetamide N-[4-[(4-acetamidophenyl)methyl]phenyl]ethanamide N,N'-(4,4'-Methylenebis(4,1-phenylene))diacetaMide |
CAS | 2719-05-3 |
Molecular Formula | C17H18N2O2 |
Molar Mass | 282.34 |
Density | 1.201±0.06 g/cm3(Predicted) |
Melting Point | 227-228 °C |
Boling Point | 564.6±43.0 °C(Predicted) |
Solubility | Soluble in DMSO (up to 30 mg/ml) |
Appearance | solid |
Color | White |
pKa | 14.73±0.70(Predicted) |
Storage Condition | Sealed in dry,2-8°C |
Stability | Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
In vitro study | In Vitro, FH1(BRD-K4477) enhances hepatocyte function and promotes maturation of differentiated intact iHeps. This may potentially alleviate a major obstacle to the adoption of iPS cells as a source of functional hepatocyte regeneration. |
Hazard Symbols | N - Dangerous for the environment |
Risk Codes | 50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. |
Safety Description | S60 - This material and its container must be disposed of as hazardous waste. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
biological activity | FH1 (BRD-K4477) is a small molecule that can promote liver cell differentiation. |